Genetic Mutations

347 articles

Having a genetic mutation can make all the difference in treatment choices, and even longer-term survival. Learn more about the importance of genetic testing and molecular profiling.

Disease Management
February 18, 2020 • 8 Min

Decoding the Differences between At-Home and Medical Genetic Testing

Genetic counselors Jill Stopfer and Heather Hampel explain the differences between at-home and medical genetic testing, including precision and knowledge.

Research
December 5, 2017 • 5 Min

The ABCs of Genetic Testing

There are a number of different genetic mutations that can cause familial pancreatic cancer. This article explains some of the most common ones.

Research
October 12, 2017 • 5 Min

Tumor Genetics Research Brings Some Answers for Families at High Risk

Professor Gloria Peterson of the Mayo Clinic is working on tumor genetics to help make early detection of pancreatic cancer a reality.

Research
November 14, 2018 • 4 Min

New NCCN Guidelines Stress Genetic Testing For All Pancreatic Cancer Patients

Genetics impact your treatment for pancreatic cancer. Dr. Sapna Syngal discusses the recommendation of genetic testing for all pancreatic cancer patients.

Research
July 2, 2020 • 4 Min

GENERATE Trial Expands Eligibility

Dr. Sapna Syngal explains the expanded eligibility standards for the GENERATE Study for genetic testing of pancreatic cancer patients and relatives.

Treatments
April 14, 2023 • 5 Min

Who Should Be Screened For Pancreatic Cancer

Who should be screened for pancreatic cancer? Dr. Allyson Ocean explains how genetic mutations and family history factor into screening.

Symptoms
October 30, 2019 • 5 Min

Studying One Family’s Mutations May Change Pancreatic Cancer Treatment and Prevention

Dr. Sahar Nissim is studying the genetic mutations in one family predisposed to pancreatic cancer, to find new ways to combat the disease.

Research
February 26, 2020 • 6 Min

Exploiting DNA Mutations For Pancreatic Cancer Treatment

Dr. James Cleary explains how the researchers at Dana-Farber are looking to make PARP inhibitors even more effective for pancreatic cancer patients.

Treatments
December 1, 2017 • 6 Min

Before You Leap: Genetic Testing for Pancreatic Cancer

Genetic counselor Megan Frone outlines the advantages of genetic testing when there is a family history of pancreatic cancer.

Research
June 19, 2023 • 7 Min

Progress in BRCA-Related Cancers Highlighted By the Basser Center

The Basser Center for BRCA hosted a panel discussion of the latest breakthroughs and discoveries for BRCA-related cancers.

Research
June 2, 2017 • 2 Min

Focusing on a Drug that Treats Specific Tumor Mutations

A clinical trial tests a signal-inhibiting drug for lung cancers with specific genetic mutations on gastrointestinal cancers with the same tumor mutations.

Research
November 1, 2018 • 5 Min

PARP Inhibitors for Pancreatic Cancer Maintenance Treatment

Dr. Kim Reiss Binder is leading a clinical trial of maintenance treatment with the PARP inhibitor rucaparib, for patients who carry the BRCA mutation.

Treatments
December 21, 2020 • 5 Min

This Versus That: Words to Know

Confused about some of the similar-sounding terms you are hearing during pancreatic cancer treatment? Our list of words to know can help.

Research
June 24, 2019 • 6 Min

GENERATE Study Aims to Improve Genetic Testing and Prevention for Pancreatic Cancer

Dr. Sapna Syngal outlines the GENERATE study, which aims to help families with a risk for pancreatic cancer by providing genetic testing.

Research
February 9, 2023 • 5 Min

PRECEDE Trial Sets Survival Rate Goal

Dr. Raymond Wadlow explains how earlier detection of high-risk people is key the PRECEDE trial’s goal to increase pancreatic cancer survival rates.